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    <title>National Microbiology Laboratory's Guide to Service</title>
    <link>http://dev.nml-lnm.gc.ca/guide2/index-eng.htm</link>
    <description>The Guide to Services provides an update to date listing of reference diagnostic services that is provided by the National Microbiology Laboratory (NML) of the Public Health Agency of Canada (PHAC).</description>
    <language>en-ca</language>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=62</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Infant pneumonia <br>
			<b>Pathogen:</b> Ureaplasma parvum <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Urethral/Urogenital swab, vaginal swab, rectal swab, urine. Nasopharygeal aspirate, throat swab or bronchioalveolar lavage may be accepted only with accompanying clinical findings supporting potential respiratory infection such as with neonatal respiratory infection.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=61</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Non-gonococcal urethritis (NGU) <br>
			<b>Pathogen:</b> Ureaplasma urealyticum <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Urethral/Urogenital swab, vaginal swab, rectal swab, urine. Nasopharygeal aspirate, throat swab or bronchioalveolar lavage may be accepted only with accompanying clinical findings supporting potential respiratory infection such as with neonatal respiratory infection.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=60</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Non-gonococcal urethritis (NGU) <br>
			<b>Pathogen:</b> Mycoplasma genitalium <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Urethral/Urogenital swab, vaginal swab, rectal swab, urine. Nasopharygeal aspirate, throat swab or bronchioalveolar lavage may be accepted only with accompanying clinical findings supporting potential respiratory infection such as with neonatal respiratory infection.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=59</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Pelvic Inflammatory Disease (PID) <br>
			<b>Pathogen:</b> Mycoplasma hominis <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Urethral/Urogenital swab, vaginal swab, rectal swab, urine. Nasopharygeal aspirate, throat swab or bronchioalveolar lavage may be accepted only with accompanying clinical findings supporting potential respiratory infection such as with neonatal respiratory infection.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=57</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Various <br>
			<b>Pathogen:</b> Mycoplasma spp. <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Swab, sputum, nasopharyngeal aspirate, urine, wound aspirate, CSF, or any other fluid appropriate to the affected area of suspicion. At least 1 mL of fluid sample is required for testing, or at least 1 mL of specimen such as swab samples re-suspended in appropriate transport medium. It is preferable if all samples are supplied in screw-capped tubes made of freeze-thaw and shatter-resistant plastic. Dry swabs are not acceptable for testing; any swabs sent must be supplied in appropriate storage medium.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=56</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Atypical pneumonia <br>
			<b>Pathogen:</b> Mycoplasma pneumoniae <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Bronchioalveolar lavage, nasopharygeal aspirate, or throat swab. Sputum, cerebrospinal fluid (CSF), and tissue samples may also be tested but are not ideal.  Dry swabs are not acceptable for testing; any swabs sent must be supplied in appropriate storage medium.  At least 1 mL of fluid sample is required for testing, and it is preferable if all samples are supplied in screw-capped tubes made of freeze-thaw and shatter-resistant plastic.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=55</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Chancroid <br>
			<b>Pathogen:</b> Haemophilus ducreyi <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> The specimen of choice for the diagnosis of chancroid is a swab that has been taken from the base of the genital ulcer. A bubo aspirate is also a suitable specimen. 

Use Dacron or cotton swabs to obtain specimens from ulcers. This is best collected by cleansing the area by flushing with sterile physiological saline, and then collecting material from the base of the ulcer using a Dacron or cotton swab.  A bubo aspirate is obtained using needle and syringe to aspirate pustular material from the bubo through normal issue.

Swabs can shipped dry OR in 1 ml Universal Transport Medium (Copan International).  Bubo aspirates should be placed in a sterile tube and shipped frozen.  Store swabs frozen until shipped for testing.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=53</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Atypical pneumonia <br>
			<b>Pathogen:</b> Chlamydophila pneumoniae <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Bronchioalveolar lavage (BAL) or lung biopsy. We may also perform testing on nasopharyngeal aspirate (NPA), sputum, and cerebrospinal fluid (CSF) however please note that these specimens are not ideal for testing.  Dry swabs are not acceptable for testing; any swabs sent must be supplied in appropriate storage medium.  At least 1 mL of fluid sample is required for testing, and it is preferable if all samples are supplied in screw-capped tubes made of freeze-thaw and shatter-resistant plastic.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Molecular Detection by PCR has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=308</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Molecular Detection by PCR <br>
			<b>Infection:</b> Respiratory psittacosis <br>
			<b>Pathogen:</b> Chlamydophila psittaci <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Molecular Detection <br>
			<b>Specimen:</b> Bronchioalveolar lavage, nasopharygeal aspirate, or throat swab. Sputum and cerebrospinal fluid (CSF) samples may also be tested but are not ideal. Please note that all culture specimen or specimen with a high risk of aerosolization WILL NOT be accepted, as these specimen are categorized and handled as CL3 organisms. Dry swabs are not acceptable for testing; any swabs sent must be supplied in appropriate storage medium.  At least 1 mL of fluid sample is required for testing, and it is preferable if all samples are supplied in screw-capped tubes made of freeze-thaw and shatter-resistant plastic.</p><hr>]]></content:encoded>
	      </item>
<item>
		<title>The Reference Diagnostic for Plasmid Profiling has been updated.</title>
	      <link>http://www.nml-lnm.gc.ca/guide2/refdiagview.php?refdiagID=148</link>
	      <content:encoded><![CDATA[<p><b>Reference Diagnostic:</b> Plasmid Profiling <br>
			<b>Infection:</b> Gonorrhea <br>
			<b>Pathogen:</b> Neisseria gonorrhoeae <br>
			<b>Laboratory:</b> Streptococcus and STI Unit <br>
			<b>Test Category:</b> Phenotyping <br>
			<b>Specimen:</b> Pure culture.</p><hr>]]></content:encoded>
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